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Panic Buying of Drugs Trump Touted as Potential COVID-19 Treatments Spark Shortages for People Who Actually Need Them

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  • Since last week, President Donald Trump has lauded chloroquine and hydroxychloroquine as potential treatment options for COVID-19.
  • While there is some evidence that supports their effectiveness against the virus, health officials warn that not enough testing has been done to approve their widespread use.
  • Still, people have begun trying to acquire the potential antiviral, leading to shortages for people who need it for it’s already approved treatments for lupus and rheumatoid arthritis.

Shortages of Hydroxychloroquine for People Who Need It

While panic buying has to lead to toilet paper and cleaning supplies shortages across the nation, it’s now also making it harder for some people to get their hands on medicine they’ve taken for years.

An influx of worried Americans are rushing to get ahold of hydroxychloroquine, a drug that treats diseases and disorders such as malaria, rheumatoid arthritis, and lupus. It’s also been hailed by President Donald Trump as an effective drug against COVID-19.

But that’s still unknown.

While there is evidence to support hydroxychloroquine or the similarly-touted chloroquine’s effectiveness against the pandemic, there is currently still not enough evidence to prove it should be used as a widespread treatment against COVID-19.

Even though both drugs have received approval from the Food and Drug Administration, the approvals are not for COVID-19. To be used on a widespread basis, the drugs would need approval following clinical trials.

Still, that hasn’t stopped some people from trying to acquire the potential antiviral by any means possible.

“Well it finally happened to me,” pharmacist Katherine Rowland said on Twitter. “A dentist just tried to call in scripts for hydroxychloroquine + azithromycin for himself, his wife, & another couple (friends). NOPE. I have patients with lupus that have been on [hydroxychloroquine] for YEARS and now can’t get it because it’s on backorder.”

According to the University of Utah, several doctors tried writing prescriptions for both themselves and for family friends to hoard in case they contracted the virus. The university refused to fill their prescriptions.
Because of stories like that, however, many people who need the drug for other conditions are finding themselves without.

According to The New York Times, 47-year-old Toni Grimes was told on Monday that she would have to wait until March 30 to refill her chloroquine prescription meant to treat her lupus. She said this is the first time she hasn’t been able to get her prescription refilled in the 13 years she’s been on it.

Grimes also runs a Phoenix-area Lupus Foundation support group and said another member also has yet to receive their refill, as well.

Such shortages have spurred the Lupus Foundation to release a statement, reading:

“The Foundation applauds the commitment of pharmaceutical companies that have pledged to increase production and supply of [vital] medications. We call on all manufacturers of hydroxychloroquine and chloroquine to do the same. However, increased production must not solely be done for the purpose of responding to COVID-19, but also to meet the existing needs of people with lupus.”

In fact, the scramble to obtain these drugs has grown so rapidly that four of the seven companies that make generic hydroxychloroquine are facing shortages. While the other three could have provided some cushion, they previously stopped making the drug altogether.

Because of the shortages, the Ohio Board of Pharmacy has banned the hoarding of these drugs. Now, people in Ohio can’t buy it unless they have lupus, rheumatoid arthritis, or a confirmed case of COVID-19.

People Are Dying Because They’re Self-Medicating

Ultimately, that may prove to be a beneficial move not only for people in Ohio who need these drugs but also for the people who don’t.

While not in the United States, reportedly, three people in Nigeria have all overdosed on the drug after self-medicating.

Because of that, Nigeria’s Centre for Disease Control issued a statement urgently warning people not to self-medicate, as such a move could lead to harm or even potential death.

In the U.S, an Arizona man died after reportedly ingesting chloroquine; however, instead of using the medical form of chloroquine, both this man and his wife took chloroquine that was supposed to be used to treat parasite infections for fish.

That woman is still alive, but she’s in critical care.

In an interview with NBC News, she said she and her husband—both of whom were in their 60’s—took it after watching several reports on television, including watching Trump laud the drug from the White House Press Room.

“I saw it sitting on the back shelf and thought, ‘Hey, isn’t that the stuff they’re talking about on TV?'” she said. “We were afraid of getting sick.”

Unfortunately, this couple’s goals were flawed from the start. Neither hydroxychloroquine nor chloroquine are being used as vaccines; rather, they are being investigated as potential antivirals. The difference here is that while vaccines prevent a person from getting the disease, antivirals are only meant to treat the disease after you already get it.

Chloroquine and Hydroxychloroquine in Clinical Trials

For widespread use, scientists need to prove that these drugs are not only effective against COVID-19 but also that the benefits outweigh the risks.

While this is a normal goal for any drug, scientists are playing especially close attention to these drugs as governments try to rapidly push them through clinical testing.

“Chloroquine is an extremely toxic drug with a terrible side effect profile,” Meghan May, a microbiologist at the University of New England College of Osteopathic Medicine, said in a written email to The New York Times. “Hydroxychloroquine is far safer, but its side effects are still significant. If it is not abundantly clear that it is beneficial, giving this drug to a critically ill patient feels risky.”

Those side effects include heart rhythm problems, severely low blood pressure, as well as muscle or nerve damage.

As reported in the journal Nature Medicine, researchers found evidence that hydroxychloroquine impedes the coronavirus’ ability to enter cells; however, that alone doesn’t mean it would do the same thing in a person or that a person could tolerate the doses used in the lab.

In a clinical trial conducted in February, scientists in China reported that chloroquine helped more than 100 patients at 10 hospitals. Because of that, the drug reportedly saw widespread use both there and in South Korea.

Still, this trial is also not enough to prove chloroquine’s effectiveness against COVID-19. Reportedly, with this study, the treated patients all had various degrees of the illness and were all treated with different doses for different amounts of time.

The trial also didn’t contain any control groups, which means that it’s also possible people could have just recovered on their own without the drug.

Another study from France has also captured many eager ears, including Trump’s. There, doctors gave hydroxychloroquine to 26 people who had been infected with the coronavirus.

Of those 26 people, six were also given an antibiotic called azithromycin, but before that study was completed, six other people dropped out. Of those, three people wound up in intensive care and one died. That’s not necessarily to say chloroquine killed them, because like that study from China, there was a lot of variation between each case. Some had been asymptomatic while others were symptomatic.

At the end of the trial, none of the six patients who had received both hydroxychloroquine and azithromycin had detectable levels of the virus. Meanwhile, over half who had received only hydroxychloroquine had no detectable levels, and only 12.5% of people who received neither drug had no detectable levels.

Once again, this single trial or even all three studies together are not enough to prove the effectiveness of these two drugs. National Institute of Allergy and Infectious Diseases Director Anthony Fauci has called such trials only anecdotal at the moment. In fact, clinical trials could take months.

Trump’s Calls for Chloroquine and Hydroxyquine

Scientists have been eyeing these drugs as potential treatments for most of the outbreak’s lifespan, but their names gained household usage after Trump announced last week that he was asking the FDA to cut “red tape” around their usage.

“It’s very powerful, but the nice part is that it’s been around for a long time so we know that if things don’t go as planned, it’s not going to kill anybody,” Trump said of chloroquine on Thursday.

Over the weekend, Trump continued to prop up those drugs, saying on Twitter, “HYDROXYCHLOROQUINE & AZITHROMYCIN, taken together, have a real chance to be one of the biggest game changers in the history of medicine… Hopefully they will….be put in use IMMEDIATELY. PEOPLE ARE DYING, MOVE FAST, and GOD BLESS EVERYONE!”

Trump announced Monday that the federal government was working to obtain large quantities of chloroquine. It has already received 3 million doses from Bayer.

On Tuesday, New York state began two trials, one focusing on chloroquine and another focusing on hydroxychloroquine with the azithromycin.

See what others are saying: (The New York Times) (NBC News) (Politico)

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Lincoln College to Close for Good After COVID and Ransomware Attack Ruin Finances

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Last year, 1,043 schools in the U.S. were the victim of ransomware attacks, including 26 colleges or universities, according to an analysis by Emsisoft.


One of the Only Historically Black Colleges in the Midwest Goes Down

After 157 years of educating mostly Black students in Illinois, Lincoln College will close its doors for good on Friday.

The college made the announcement last month, citing financial troubles caused by the coronavirus pandemic and a ransomware attack in December.

Enrollment dropped during the pandemic and the administration had to make costly investments in technology and campus safety measures, according to a statement from the school.

A shrinking endowment put additional pressure on the college’s budget.

The ransomware attack, which the college has said originated from Iran, thwarted admissions activities and hindered access to all institutional data. Systems for recruitment, retention, and fundraising were completely inoperable at a time when the administration needed them most.

In March, the college paid the ransom, which it has said amounted to less than $100,000. But according to Lincoln’s statement, subsequent projections showed enrollment shortfalls so significant the college would need a transformational donation or partnership to make it beyond the present semester.

The college put out a request for $50 million in a last-ditch effort to save itself, but no one came forward to provide it.

A GoFundMe aiming to raise $20 million for the college only collected $2,452 as of Tuesday.

Students and Employees Give a Bittersweet Goodbye

“The loss of history, careers, and a community of students and alumni is immense,” David Gerlach, the college’s president, said in a statement.

Lincoln counts nearly 1,000 enrolled students, and those who did not graduate this spring will leave the institution without degrees.

Gerlach has said that 22 colleges have worked with Lincoln to accept the remaining students, including their credits, tuition prices, and residency requirements.

“I was shocked and saddened by that news because of me being a freshman, so now I have to find someplace for me to go,” one student told WMBD News after the closure was announced.

When a group of students confronted Gerlach at his office about the closure, he responded with an emotional speech.

“I have been fighting hard to save this place,” he said. “But resources are resources. We’ve done everything we possibly could.”

On April 30, alumni were invited back to the campus to revisit the highlights of their college years before the institution closed.

On Saturday, the college held its final graduation ceremony, where over 200 students accepted their diplomas and Quentin Brackenridge performed the Lincoln Alma Mater.

Last year, 1,043 schools in the U.S. were the victim of ransomware attacks, including 26 colleges or universities, according to an analysis by Emsisoft.

See what others are saying: (The New York Times) (Herald Review) (CNN)

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U.S. Tops One Million Coronavirus Deaths, WHO Estimates 15 Million Worldwide

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India’s real COVID death toll stands at about 4.7 million, ten times higher than official data, the WHO estimated.


One Million Dead

The United States officially surpassed one million coronavirus deaths Wednesday, 26 months after the first death was reported in late February of 2020.

Experts believe that figure is likely an undercount, since there are around 200,000 excess deaths, though some of those may not be COVID-related.

The figure is the equivalent of the population of San Jose, the tenth-largest city in the U.S., vanishing in just over two years. To put the magnitude in visual perspective, NECN published a graphic illustrating what one million deaths looks like.

At the beginning of the pandemic, the White House predicted between 100,000 and 240,000 Americans would die from the coronavirus in a best-case scenario.

By February 2021, over half a million Americans had died of COVID.

The coronavirus has become the third leading cause of death in the U.S. behind heart disease and cancer.

The pandemic’s effects go beyond its death toll. Around a quarter of a million children have lost a caregiver to the virus, including about 200,000 who lost one or both parents. Every COVID-related death leaves an estimated nine people grieving.

The virus has hit certain industries harder than others, with food and agriculture, warehouse operations and manufacturing, and transportation and construction seeing especially high death rates.

People’s mental health has also been affected, with a study in January of five Western countries including the U.S. finding that 13% of people reported symptoms of PTSD attributable to actual or potential contact with the virus.

Fifteen Million Dead

On Thursday, the World Health Organization estimated that nearly 15 million people have died from the pandemic worldwide, a dramatic revision from the 5.4 million previously reported in official statistics.

Between January 2020 and the end of last year, the WHO estimated that between 13.3 million and 16.6 million people died either due to the coronavirus directly or because of factors somehow attributed to the pandemic’s impact on health systems, such as cancer patients who were unable to seek treatment when hospitals were full of COVID patients.

Based on that range, scientists arrived at an approximate total of 14.9 million.

The new estimate shows a 13% increase in deaths than is usually expected for a two-year period.

“This may seem like just a bean-counting exercise, but having these WHO numbers is so critical to understanding how we should combat future pandemics and continue to respond to this one,” Dr. Albert Ko, an infectious diseases specialist at the Yale School of Public Health who was not linked to the WHO research, told the Associated Press.

Most of the deaths occurred in Southeast Asia, Europe, and the Americas.

According to the WHO, India counts the most deaths by far with 4.7 million, ten times its official number.

See what others are saying: (NBC) (U.S. News and World Report) (Scientific American)

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Official Says Missing Alabama Convict and Corrections Officer Had a “Special Relationship”

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Authorities have also said they now believe the officer willfully helped the inmate escape.


New Information on Missing Inmate & Officer

Authorities in Alabama revealed Tuesday that Assistant Director of Corrections for Lauderdale County Vicky White, who is accused of helping a murder suspect Casey Cole White escape from jail, had a “special relationship” with the inmate.

“Investigators received information from inmates at the Lauderdale County Detention Center over the weekend that there was a special relationship between Director White and inmate Casey White,” Lauderdale County Sheriff Rick Singleton said in a statement. “That relationship has now been confirmed through our investigation by independent sources and means.”

Officials have previously said that the two are not related, despite their shared surname.

Singleton elaborated on the nature of the relationship while speaking to CNN later on Tuesday. He said it took place “outside of her normal work hours” and added that although it did not include “physical contact,” he still characterized it as “a relationship of a different nature.”

“We were told Casey White got special privileges and was treated differently while in the facility than the other inmates,” Singleton said.

Also on Tuesday, the Marshals Service issued a statement confirming that authorities believe Officer White had helped Mr. White escape. The authorities described her as a “wanted fugitive” and offered a $5,000 reward for any information on her whereabouts. Earlier this week, the Marshals Service also offered a $10,000 reward for any information that could lead to Mr. White’s capture.

Singleton echoed the belief that Officer White’s actions were intentional while speaking to Good Morning America Wednesday.

“I think all of our employees and myself included were really hoping that she did not participate in this willingly. But all indications are that she absolutely did,” he said. “We’re very disappointed in that because we had the utmost trust in her as an employee and as an assistant director of corrections.”

Mysterious Escape

Vicky White and Casey White were last seen leaving the Lauderdale County jail just after 9:30 a.m. Friday. The officer told other employees that she was taking the inmate to a mental health evaluation at a courthouse just down the road, and that she would be going to a medical appointment after because she was not feeling well.

Officials later said her actions violated an official policy that required two sworn deputies to transport people with murder charges. In 2020, Mr. White was charged with two counts of capital murder in connection to a fatal stabbing he confessed to and was awaiting his trial in Lauderdale County.

Mr. White was also serving time for what officials said was a “crime spree” in 2015 which included home invasion, carjacking, and a police chase. He had also previously tried to escape from jail, police said.

It wasn’t until 3:30 p.m. on Friday that a jail employee reported to higher-ups that he was not able to reach Officer White on her phone and that Mr. White had never been returned to his cell.

During a press conference that same night, Singleton told reporters that there had never even been a scheduled mental health evaluation. At another briefing Monday, he announced that an arrest warrant had been issued for Vicky on a charge of “permitting or facilitating an escape in the first degree.”

At the time, Singleton said it was unclear “whether she did that willingly or was coerced or threatened” but added, “we know for sure she did participate.” 

See what others are saying: (CNN) (ABC News) (NPR)

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